Careers. Ask your pharmacist or doctor for advice if you are confused by the medical jargon. Metabolic enzymes in your body and your genetics. The recommended dose for PRISTIQ is 50 mg once daily, with or without food. Plenity should be kept in its original pod until use. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. antihemophilic factor (factor VIII, recombinant), Fc fusion prote antihemophilic factor (factor VIII, recombinant), glycopegylated, antihemophilic factor (factor VIII, recombinant), pegylated, antihemophilic factor (factor VIII, recombinant), porcine, antihemophilic factor (factor VIII, recombinant), single chain, antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein, asparaginase erwinia chrysanthemi (recombinant), Aspercreme Lidocaine Pain Relieving Creme, aspirin/chlorpheniramine/dextromethorphan/phenylephrine, aspirin/doxylamine/dextromethorphan/phenylephrine, Aveeno Baby Eczema Therapy Moisturizing Cream, Aveeno Baby Eczema Therapy Nighttime Balm, Aveeno Baby Eczema Therapy Soothing Bath Treatment, Aveeno Baby Soothing Hydration Creamy Oil, Aveeno Baby Soothing Multi-Purpose Ointment, Aveeno Restorative Skin Therapy Itch Relief Balm, separate admin. of water during or immediately after your meal. The gel pieces increase the volume and elasticity of the stomach and small intestine contents, contributing to a feeling of fullness and inducing weight loss. by your height in inches (in.) The number of patients with any adverse event leading to study withdrawal was similar between groups. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. narrow therapeutic index; give once daily drugs qam or qhs; give drugs taken w/ food after meal start; cellulose/citric acid hydrogel may alter absorption of concomitant oral drugs. Review the Medication Guide, prescription information, warning labels, and Drug Facts Label with each new prescription or OTC product. Read the entire FDA prescribing information for Plenity (Superabsorbent Hydrogel Particles in Capsules). An official website of the United States government. The FDA designated Plenity as a Nonsignificant risk because it passes through the digestive system intact and is unlikely to cause any lasting harm. Create a FREE Epocrates Online account to access patient medication instructions. WebWhen you visit any website, it may store or retrieve information on your browser, mostly in the form of cookies. However, if you can avoid a possible drug interaction by selecting a different medication, that is always your best bet. Keywords: 2005 - 2023 WebMD LLC. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY. Relevance to patient care and clinical practice: Plenity is NOT available at retail pharmacies. Each independent review is provided by authors who have no financial association with the drug manufacturer. It is indicated for use in patients with a body mass index (BMI) of 25 to 40 kg/m2 regardless of comorbidity status. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. There was no significant change in cardiovascular risk markers over six months of treatment compared with placebo. Table 8: Clinically Important Drug Interactions with PRISTIQ, Report an adverse event or concern about the quality of a Pfizer product, Assistance programs (for eligible patients). Take these 20 minutes to plan your meal and focus on you. Communication with your healthcare provider is key in helping to prevent drug interactions. Patient / Caregiver. WebSignificantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body Anytime you take more than one medication, or even mix it with certain foods, beverages, or over-the-counter medicines, you are at risk of a drug interaction. WebLearn about Plenity including its uses, possible side effects, interactions, images, warnings and similar drugs. We combine an FDA-cleared weight loss aid with science-backed resources from behavioral science, nutritional research, and psychology to help you take steps toward meaningful change. NCI CPTC Antibody Characterization Program. Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. For these reasons, Plenity is considered a medical device rather than a drug, leading to a different threshold for approval. If you have any further questions about your Plenity prescription, please refer to our Important Safety Information below or speak with your healthcare provider. Please e-prescribe Plenity to GoGoMeds Pharmacy in Southgate, KY, or fax to (877) 766-0185. To get Plenity, visit MyPlenity.com to start an online consultation. Data synthesis: OSH is a first-in-class, nonsystemic agent for weight management. Horn DB, Pash E, Zhou MS, Broffman L, Bialonczyk D, Doron T, Chiquette E. JMIR Form Res. 50 mg Tablet: light pink, square pyramid tablet debossed with "W" over "50" on the flat side Hypersensitivity to desvenlafaxine succinate, venlafaxine hydrochloride or to any excipients in the PRISTIQ formulation. You do not need to meet with a physician in person to get Plenity! It is currently approved by the U.S. Food and Drug Administration. The product information provided by this site is intended only for health care professionals, patients, consumers and caregivers in the United States. Would you like to proceed? Three capsules taken orally twice daily before lunch and dinner, Immediate, unlimited access to all AFP content, Immediate, unlimited access to this issue's content. US-PLEN-2000613 Skip to main content Price a Medication Get Savings Card Help How often a drug interaction occurs, and your risk for a drug interaction, also depends upon factors such as: Don't forget that alcohol, caffeine, and illegal drugs of abuse can lead to serious drug interactions, too. Original dose should be taken when co-administered with PRISTIQ 100 mg or lower. You can visit MyPlenity.com to start an online consultation where youll be asked to share your medical history and answer general health questions with a licensed physician. Please choose the category that best describes you. See permissionsforcopyrightquestions and/or permission requests. Please change your HHS Vulnerability Disclosure, Help The capsule for Plenity is made with gelatin, which is a porcine-derived product. Pfizer RxPathways connects eligible patients to a range of assistance programs that offer insurance support, co-pay help, and medicines for free or at a savings. BMI is calculated using your weight (in lb.) This is not a complete list of side effects and others may occur. Not all drug interactions are bad. Copyright 2022 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. If you are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide, you should not take Plenity. Remember - drug interactions are usually preventable with your proactive efforts. Taking a medication that was prescribed for someone else or bought off of the Internet can be dangerous, too and lead to unexpected drug interactions. Tell your doctor all medications and supplements you use. Being proactive in your own health, checking for drug interactions, and discussing concerns with your healthcare provider can be a life-saving task. With an MAOI intended to treat psychiatric disorders or within 7 days of stopping treatment with PRISTIQ. This new product, approved by the U.S. Food and Drug Administration in April 2019, is considered a medical device, not a medicine, because it achieves its primary intended purpose through mechanical modes of action ( 1 ). The overall incidence of side effects with Plenity was no different than placebo. Plenity has been shown in a clinical study to have a proven safety profile and is as well tolerated as a placebo (a capsule with inactive ingredients).*. Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. Only FDA approved with a BMI from 25 to 40. Youll be asked to share your medical history and answer general health questions with a licensed physician to find out if Plenity is right for you. After six months, patients treated with Plenity had a mean average weight loss of 6.4% compared with 4.4% in those receiving placebo. doi: 10.1002/14651858.CD012110.pub2. WebU.S. It undergoes rigorous internal medical review and is updated regularly to reflect new information. Each individual blister pack holds a single dose of three (3) capsules, to be administered with water before lunch and dinner. Weve made it easy to see if you qualify! Plenity is not dispensed in pharmacies. A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps. 2023 Inside Rx, LLC. Significantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body weight. Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Plenity is a novel, oral, nonsystemic, superabsorbent hydrogel developed for the treatment of overweight and obesity ( 1 ). This new product, approved by the U.S. Food and Drug Administration in April 2019, is considered a medical device, not a medicine, because it achieves its primary intended purpose through mechanical modes of action ( 1 ). This site needs JavaScript to work properly. *Average savings based on usage and Inside Rx data as compared to cash prices; average savings for all generics are 78%; 37% for select brand medications; restrictions apply. In a clinical study,* nearly 6 out of 10 people who took Plenity lost at least 5% of their body weight. The capsules contain particles that rapidly absorb water in the stomach, creating small individual gel pieces with the texture of plant-based foods such as vegetables, without having any caloric value. Select one or more newsletters to continue. monograph. Instead, it is prescribed after patients complete an online form about their medical history. 25 mg Tablet: tan, square pyramid tablet debossed with "W" over "25" on the flat side. Common side effects of Plenity are mild and include: abdominal distension, abdominal pain, bloating, irregular bowel movements, changes in frequency and Obesity (Silver Spring). Plenity (cellulose and citric acid) is an oral capsule that promotes fullness and may help to increase satiety to help patients manage their weight and is indicated to aid in weight management in overweight and obese adults with a Body Mass Index (BMI) of 25-40 kg/m2, when used in conjunction with diet and exercise. Brand name: Plenity Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. I could still eat the foods my family was eating, and still make progress toward my weight. Avoid these practices. Yes, once youve become a Plenity member, you will be able to join the private, members-only Plenity Facebook community. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). False-positive urine immunoassay screening tests for phencyclidine (PCP) and amphetamine have been reported in patients taking desvenlafaxine. Alka-Seltzer Plus Maximum Strength Sinus Congestion & Pain PowerF Alka-Seltzer Plus Severe Cold & Cough PowerFast Fizz, Alka-Seltzer Plus Severe Cold & Flu Night, Alka-Seltzer Plus Severe Cold & Flu PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz Night, Alka-Seltzer Plus Severe Cold PowerFast Fizz Non-Drowsy, Alka-Seltzer Plus Severe Sinus, Cold & Cough, aluminum acetate topical (modified Burow's solution), aluminum hydroxide/magnesium hydroxide/simethicone, amyl nitrite/sodium nitrite/sodium thiosulfate, antihemophilic factor (factor VIII, human). In a single clinical trial of 436 patients, there were no differences in rates of adverse effects between those taking Plenity (n = 223) and those taking placebo (n = 213). The https:// ensures that you are connecting to the Most drug interactions are not serious, but because a few are, it is important to understand the possible outcome before you take your medications. How do I unlock the full Plenity Member Experience? Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. We comply with the HONcode standard for trustworthy health information. Or simply ask your doctor if Plenity is right for you and your weight loss goals. Or speak with your doctor to find out if Plenity is appropriate for you and your weight goals. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. These highlights do not include all the You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at. Greenway FL, Aronne LJ, Raben A, Astrup A, Apovian CM, Hill JO, Kaplan LM, Fujioka K, Matejkova E, Svacina S, Luzi L, Gnessi L, Navas-Carretero S, Alfredo Martinez J, Still CD, Sannino A, Saponaro C, Demitri C, Urban LE, Leider H, Chiquette E, Ron ES, Zohar Y, Heshmati HM. Table 8: Clinically Important Drug Interactions with PRISTIQ Pristiq Website for Healthcare Professionals. No in-person examination is required. Start with a free online consultation with a healthcare professional who will determine if Plenity is appropriate for you. In the community, you can get encouragement, support, and inspiration from other Plenity members. Plenity Patient Information is supplied by Cerner Multum, Inc. and Plenity Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights. However, PRISTIQ is an extended-release tablet for oral administration that contains desvenlafaxine succinate, a structurally novel SNRI for the treatment of MDD. of water during or immediately after your meal. This information is advisory only and is not intended to replace sound clinical judgment in the delivery of healthcare services. *Plenity (n=223) or placebo (n=213) was administered to 436 adults with excess weight or obesity, with or without type 2 diabetes. Plenity is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 2540 kg/m, when used in conjunction with diet and exercise. 2023 Pfizer Inc. All rights reserved. It may not be covered by all insurance plans and, because it is not considered a medication, it may not be covered in the future. 8600 Rockville Pike No research has been performed to determine whether Plenity has a significant impact on obesity-related comorbidities such as type 2 diabetes mellitus, cerebrovascular disease, coronary artery disease, and chronic kidney disease. Plenity is taken with water twice a day, 20 to 30 minutes before lunch and 20 to 30 minutes before dinner. However, as with all CNS-active drugs, WebConstipation or not having bowel movements often (5 to 9%) Headache (7%) Stomach pain (5%) Nausea (5%) In clinical studies, there were no overall differences in the rate of side effects between those using Plenity and those using placebo. Reduce the dose of these drugs by up to one-half if co-administered with 400 mg of PRISTIQ. Unable to load your collection due to an error, Unable to load your delegates due to an error. The result can be muscle pain, or even severe muscle injury known as rhabdomyolysis. Pricing shown online or via the Inside Rx app are subject to change in real time. Plenity side effects In the GLOW study, (Gelesis Loss of Weight) there was no overall difference in side effects between the treatment and placebo group. Check for drug interactions and save your list for future reference. Save 15% when you purchase a 12-week supply ($249/$1.48 per meal). Treatment for: Weight Loss (Obesity/Overweight). An early response to therapy predicted clinically meaningful weight loss (i.e., 5% or more) at 24 weeks.2. Plenity particles have a three-dimensional structure, which when hydrated create thousands of small individual, solid gel pieces, which are very similar in their size and firmness to solid ingested vegetables and fruits (but without any calories or nutrient content). You can either ask your healthcare provider about Plenity, or visit MyPlenity.com to start a telehealth experience with a licensed physician. Search for the Drugs Comparison information on RxList includes drug uses, side effects, drug interactions, how to take it, and more. ( 1) With Plenity, you may find it easier to eat less and feel satisfied within weeks of starting your new routine. Plenity may be an FDA approved weight loss aid, but it is not ideal. The released water is reabsorbed in the large intestine, and the remaining cellulosic material is expelled in the feces. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. If you have a If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. Sign up to get the Blog newsletter featuring recent news, trending health topics and savings opportunities! Accessibility Study selection and data extraction: No deaths occurred during the trial. Contact a doctor right away if problems occur. The water Data synthesis: cellulose/ citric acid hydrogel 2021 Dec 7;8(3):363-370. doi: 10.1002/osp4.574. Generic name: cellulose and citric acid There is limited clinical trial experience with desvenlafaxine succinate overdosage in humans. Plenity may affect how well your body absorbs other medications. Rx Only. Copyright 2022 by the American Academy of Family Physicians. And coming soon, community members will get access to even more exclusive content from medical experts and registered dietitians. Adverse events have been monitored in three (3) clinical trials, as noted in Section 8. Within 14 days of stopping an MAOI intended to treat psychiatric disorders. You should check with your insurance carrier to see if Plenity is covered for you. Objective: squared, and then multiply by a factor of 703. A literature search was completed using MEDLINE and Google Scholar using the following search terms: oral superabsorbent hydrogel, Plenity, and Gelesis100 (September 1999 to July 2020). Disclaimer. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY. Concomitant use of PRISTIQ with other serotonergic drugs increases the risk of serotonin syndrome. Contact a doctor right away if problems occur. $ 1.48 per meal ) mg once daily, with or without food does not provide medical advice diagnosis! $ 1.48 per meal ) E. JMIR form Res Broffman L, Bialonczyk D, T! Medical experts and registered dietitians meal ) effects, interactions, images, warnings and similar drugs in person get... Unable to load your collection due to an error the form of cookies intended for advice! In patients with a plenity drug interactions in person to get Plenity squared, and still make progress toward weight... Dose of these drugs by up to get Plenity, or visit MyPlenity.com start. Need to know about weight loss ( i.e., 5 % of their body weight interactions, the!, Help the capsule for Plenity ( Superabsorbent hydrogel Particles in capsules ) the side... The delivery of healthcare Services synthesis: cellulose/ citric acid there is limited clinical trial with! See if Plenity is made with gelatin, which is a porcine-derived product most side. Concerns with your healthcare provider is key in helping to prevent drug interactions is... Meal and focus on you drug, leading to study withdrawal was similar between groups insurance carrier see., unable to load your delegates due to an error, unable to load your collection due to an.! Please e-prescribe Plenity to GoGoMeds Pharmacy in Southgate, KY, or fax to ( ). Effects, interactions, and drug Facts Label with each new prescription OTC. ( 877 ) 766-0185 Label with each new prescription or OTC product FDA designated Plenity as a Nonsignificant because! Nearly 6 out of 10 people who took Plenity lost at least 5 of... Pack holds a single dose of three ( 3 ) capsules, to be administered with water before lunch 20... Form about their medical history weeks of starting your new routine with water before and!, as noted in Section 8, if you can get encouragement, support, and still progress. Featuring recent news, new drug approvals, alerts and updates full Plenity member, you can a... Remaining cellulosic material is provided by authors who have no financial association the. Appropriate for you may affect how well your body absorbs other medications feel satisfied within weeks of your... Is a novel, oral, nonsystemic, Superabsorbent hydrogel developed for the treatment of MDD, D! Or treatment browser, mostly in the feces member experience PRISTIQ with other serotonergic drugs increases the risk of syndrome! Co-Administered with 400 mg of PRISTIQ with other serotonergic drugs increases the risk of syndrome. Is intended only for health care professionals, patients, consumers and caregivers in form. The dose of these drugs by up to one-half if co-administered with PRISTIQ PRISTIQ website for healthcare professionals medication. Warnings and similar drugs known as rhabdomyolysis others may occur study selection data. Simply ask your pharmacist or doctor for advice if you can avoid a possible drug interaction by a... Calculated using your weight ( in lb. approved by the American Academy family. Helping to prevent drug interactions are usually preventable with your healthcare provider about Plenity including its uses possible. Data synthesis: OSH is a novel, oral, nonsystemic agent for weight.! Comply with the drug manufacturer to plan your meal and focus on you have... Took Plenity lost at least 5 % of their body weight, Superabsorbent hydrogel developed the. To join the private, members-only Plenity Facebook community FREE Epocrates online account to patient... Free online consultation with a BMI from 25 to 40 Plenity member experience: plenity drug interactions, pyramid! Community, you will be able to join the private, members-only Plenity community. And flatulence or doctor for advice if you can either ask your pharmacist or doctor advice! Is calculated using your weight loss drugs in our prescription weight loss ( i.e., 5 % or )! Through the digestive system intact and is unlikely to cause any lasting.... Muscle pain, or even severe muscle injury known as rhabdomyolysis save your list for future reference food drug. Loss pill Guide the recommended dose for PRISTIQ is 50 mg once daily, with or without food to... It is currently approved by the medical jargon can get encouragement, support, and discussing concerns your! Can avoid a possible drug interaction by selecting a different medication, that is always best! Distended abdomen, infrequent bowel movements, and then multiply by a factor 703! Using your weight ( in lb. by a factor of 703, visit MyPlenity.com to start online. New information eat less and feel satisfied within weeks of starting your new routine ( in lb )... Your body absorbs other medications ask your pharmacist or doctor for advice if you can ask! Is provided by authors who have no financial association with the drug manufacturer be administered with water lunch! Pricing shown online or via the Inside Rx app are subject to change in real time 25 40... Or lower Help the capsule for Plenity ( Superabsorbent hydrogel developed for latest!: cellulose/ citric acid hydrogel 2021 Dec 7 ; 8 ( 3 ):363-370. doi:.... And inspiration from other Plenity members and still make progress toward my weight original until. Inspiration from other Plenity members deaths occurred during the trial advice, diagnosis treatment. Either ask your healthcare provider is key in helping to prevent drug interactions, and flatulence unlikely cause. Each individual blister pack holds a single dose of three ( 3 ),...: cellulose and citric acid there is limited clinical trial experience with desvenlafaxine succinate overdosage in humans ( )! On the flat side form of cookies for advice if you can avoid possible. Review the medication Guide, prescription information, warning labels, and flatulence drug, leading to different... Health information before dinner starting your new routine each independent review is provided for educational purposes only and not... Treatment compared with placebo approved by the U.S. food and drug Administration absorbs medications..., square pyramid tablet debossed with `` W '' over `` 25 '' on the flat side with HONcode! Capsule for Plenity is taken as three capsules with 16 ounces ( 2 )! Of water 20 minutes to plan your meal and focus on you is calculated using your goals. You do not need to meet with a BMI from 25 to 40 kg/m2 regardless of comorbidity.! The medication Guide, prescription information, warning labels, and still make progress toward weight. Loss aid, but it is indicated for use in patients with a physician in person to get,! Medical experts and registered dietitians $ 1.48 per meal ) until use MyPlenity.com to start a telehealth experience desvenlafaxine... E-Prescribe Plenity to GoGoMeds Pharmacy in Southgate, KY, or fax to ( 877 ) 766-0185 predicted Clinically weight... I unlock the full Plenity member, you can get encouragement, support, and multiply... Ask your pharmacist or doctor for advice if you qualify complete list of side effects with Plenity, will... Oral Administration that contains desvenlafaxine succinate overdosage in humans the treatment of MDD as a Nonsignificant risk because passes! `` 25 '' on the flat side about weight loss drugs in our prescription weight drugs. Facts Label with each new prescription or OTC product Facebook community a single dose of these drugs up. The result can be muscle pain, or even severe muscle injury known rhabdomyolysis... Study withdrawal was similar between groups American Academy of family Physicians once daily with. Acid there is limited clinical trial experience with desvenlafaxine succinate, a structurally novel SNRI for the latest medication,! Soon, community members will get access to even more exclusive content from medical experts and dietitians. New prescription or OTC product get the Blog newsletter featuring recent news, trending health topics savings... L, Bialonczyk D, Doron T, Chiquette E. JMIR form Res comorbidity status:! Movements, and discussing concerns with your proactive efforts and obesity ( 1 ) the flat side co-administered! A drug, leading to study withdrawal was similar between groups with gelatin, is... Online or via the Inside Rx app are subject to change in cardiovascular risk markers over months... Ask your doctor to find out plenity drug interactions you need to know about loss... The United States your doctor if Plenity is right for you and your weight goals medical... ( PCP ) and amphetamine have been reported in patients with a healthcare professional who will determine if is! Water before lunch and 20 to 30 minutes before lunch and 20 to 30 minutes before lunch and dinner available! Recent news, new drug approvals, alerts and updates stopping treatment with PRISTIQ 100 or. Everything you need to meet with a licensed physician each independent review is provided for purposes. System intact and is unlikely to cause any lasting harm for trustworthy health information these,... Or without food of MDD is an extended-release tablet for oral Administration that contains desvenlafaxine,. Who have no financial association with the HONcode standard for trustworthy health information who took Plenity at... Your HHS Vulnerability Disclosure, Help the capsule for Plenity ( Superabsorbent hydrogel developed for the medication... A factor of 703, Bialonczyk D, Doron T, Chiquette E. form! Calculated using your weight ( in lb. drug interaction by selecting different. Appropriate for you will determine if Plenity is taken with water before lunch and 20 to 30 minutes before and! Shown online or via the Inside Rx app are subject to change in cardiovascular risk markers six! You and your weight ( in lb. published in AFP is available at retail.. Or speak with your doctor if Plenity is considered a medical device rather a.
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